Articles - Tagged as 'Latin America'

Study protocol for the multicentre cohorts of Zika virus infection in pregnant women, infants, and acute clinical cases in Latin America and the Caribbean: the ZIKAlliance consortium

Results of large cohort studies will provide better risk estimates for birth defects and other developmental abnormalities associated with ZIKV infection including possible co-factors for the variability of risk estimates between other countries and regions. Additional outcomes include incidence and transmission estimates of ZIKV during and after pregnancy, characterization of short and long-term clinical course following infection and viral kinetics of ZIKV.

Complex Scenario of Homotypic and Heterotypic Zika Virus Immune Enhancement

Letter to the Editor

Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis

The findings in this article suggest that the ZIKV epidemic is by and large over within LAC, with incidence projected to be low in most cities in 2018. Local low levels of transmission are probable, but the estimated rate of infection suggests that most cities have a population with high levels of herd immunity.

How Did Zika Virus Emerge in the Pacific Islands and Latin America?

Based on comparative ZIKV complete genome phylogenetic analyses and temporal estimates, the authors identify amino acid substitutions that may be associated with increased viral epidemicity, CZVS, and GBS. Reverse genetics, vector competence, and seroepidemiological studies will test the hypothesis that these amino acid substitutions are determinants of epidemic and neurotropic ZIKV emergence.